Keep It Up! 2.0


The logo for Keep It Up! 2.0. At the top it says "HAVE FUN. STAY SAFE."Keep It Up! 2.0 (KIU! 2.0) is a multisite randomized control trial comparing two versions of an online HIV prevention program for young men who have sex with men (YMSM). The intervention is based on the Information-Motivation-Behavior Skills Model for HIV risk behavior change, principals of E-learning, and qualitative research with ethnically diverse YMSM. KIU! 2.0 is being conducted by researchers at Northwestern University in Chicago, Hunter College in New York City, and Emory University in Atlanta with support from community clinic partners in the three cities.

The KIU! 2.0 study has three specific aims:

  1. Integrate the KIU! intervention into a widely-used health technology platform to increase its scalability, adaptability, and potential for broad implementation.
  2. Test the efficacy of the KIU! e-Health intervention in a multisite RCT that meets CDC criteria for “best evidence interventions.”
  3. Explore if the KIU! intervention has differential efficacy across important subgroups of YMSM.

A total of 900 ethnically diverse YMSM were enrolled from online advertising and clinics such as Vida/SIDA, Center on Halsted, Brothers Health Collective, and Howard Brown in Chicago; Callen-Lorde, Gay Men of African Descent (GMAD), Gay Men’s Health Crisis (GMHC), and Harlem United in New York; and AID Atlanta and Ric Crawford in Atlanta.

KIU! 2.0 is currently closed to enrollment. Follow-up data collection is tentatively scheduled to be completed by Spring 2017.

Investigator:  Dr. Brian Mustanski
Co-Investigators:  Drs. George J. Greene, Jeffrey T. Parsons, and Patrick S. Sullivan
Funder:  National Institute on Drug Abuse